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Technical Information Magazine 202303-01 Comprehensive Analysis of Biomolecular Interactions

This paper presents a comprehensive analysis of interactions using multiple methods, including surface plasmon resonance and isothermal titration calorimetry.

The technical information magazine The TRC News provides the latest information on analytical techniques that are useful for research and development, solving production troubles, and quality control. [Abstract] Molecular interaction analysis is an indispensable method in the study of life phenomena and the development of therapeutic drugs. The information on interactions obtained by different methods varies; for instance, surface plasmon resonance provides kinetic parameters of interactions, while isothermal titration calorimetry can acquire thermodynamic parameters of interactions. This paper introduces comprehensive analysis cases of interactions using multiple methods through multifaceted analysis. [Table of Contents] 1. Introduction 2. Surface Plasmon Resonance / Isothermal Titration Calorimetry 3. Analysis of the Interaction between STING and cGAMP 4. Conclusion

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